Leishmaniasis in dogs is a widespread disease that causes protozoans of the Trypanosomatidae family.
An animal can infect it after a mosquito bite - a carrier of leishmaniasis pathogens.
Moreover, the incubation period of this disease can last from several weeks to several months. Leishmaniasis is dermal and visceral with lesions of the spleen, liver, lymph nodes, bone marrow, etc.
Symptoms of leishmaniasis in dogs
With the cutaneous form of the disease, nodules appear on the site of the parasite introduction, which eventually turn into ulcers. Also on the skin appear patches of baldness. Most often suffer from the ears, the area around the eyes and on the back of the nose .
Usually this form of invasion takes place chronically from year to year, but the animal does not die from it. Visceral leishmaniasis is much more difficult. This form of the disease can be both acute and chronic and is characterized by the defeat of fever, the reticuloendothelial system, the oppression of the animal and its severe thinning.
Also , the dog is progressing conjunctivitis , anemia, and often a digestive function disorder. Faeces in an animal have an admixture of blood and mucus. Ulcers appear on the head. Paralysis and paresis may occur, hemodynamics is disturbed. Parasites and products of their vital activity destroy the cells of the body, cause toxic and allergic reactions.
Leishmania reproduce in the bone marrow and lymph nodes, so there is an increase in the spleen, liver and lymph nodes. The acute course of the disease occurs more often in young dogs up to 3 years. Typically, the animal dies a few months after the first symptoms of the disease. Although there are cases of recovery.
Treatment of the disease
There are several foreign chemo drugs that give positive results. The sodium antimonigluconate (sodium stibogluconate) is given for 10 days in a dose of 10-20 mg per kilogram of dog weight per day. Then you need to take a break for 10 days and repeat the treatment.
Methylglucamine antimonium or glucantim in the form of a 30% solution is used intramuscularly in a dose of 5-20 ml. But they are not given every day, but every 2-3 days. The total medication is given 8 to 12 times, maximum (in neglected cases) - up to 20 times.
Pentamidine (lomidin) is administered intramuscularly every two days at a dose of 2-4 mg per kilogram of body weight of the dog, gradually increasing the dose. Complete recovery should occur after 15-20-fold application of the drug. However, at the injection site, muscle necrosis can be observed.